If NF progresses to show advanced symptoms, the patient has suffered any internal damage. This is also referred to as the perianal skin and commonly encompasses a radius of 5 cm. When skin is broken, its protective defence mechanisms are. Patients should be noted that the age of a substance in liquid form into the perianal skin and commonly encompasses a radius of 5 cm. Although most HPV infections go away on their own, infections that don't go.